产品货号：
Z32698
中文名称：
Caveolin-1/CAV1抗体
英文名称：
Anti-Caveolin-1/CAV1 Antibody (Clone#12C7)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Caveolin-1/CAV1 Antibody (Clone#12C7) |
| 指标别名 | BSCL3;CAV;CAV1;Caveolin 1;Caveolin-1;CGL3;MSTP085;VIP21 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,IHC-F,IF |
| 基因名称 | CAV1 |
| 克隆号 | 12C7 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2a |
| 免疫原 | E.coli-derived human Caveolin-1 recombinant protein (Position:G4-I178).Human Caveolin-1 shares 95% and 94% amino acid (aa) sequence identity with mouse and rat Caveolin-1,respectively. |
| 实际分子量 | 22KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | CAV1(Caveolin-1) is a protein that in humans is encoded by the CAV1 gene.The CAV1 gene is mapped to 7q31.2.The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types.The protein links integrin subunits to the tyrosine kinase FYN,an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression.The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade.CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex.By using alternative initiation codons in the same reading frame,two isoforms(alpha and beta) are encoded by a single transcript from this gene. |
| Uniprot ID | Q03135 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section 1:50～400 Immunofluorescence (IF) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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